%0 Journal Article %T Influence of Antineoplastic Safe Handling Guidelines on Enhancing Nurses’ Performance %J Egyptian Journal of Health Care %I Ain Shams University, Faculty of Nursing %Z 1687-9546 %A Moustafa Elpasiony, Nafisa %A Said Abdelhady Garf, Faten %A Ali Hafez, Ahmed %A Ramadan Ahmed, Shimaa %D 2022 %\ 12/01/2022 %V 13 %N 4 %P 1293-1307 %! Influence of Antineoplastic Safe Handling Guidelines on Enhancing Nurses’ Performance %K antineoplastic drugs %K safe handling guidelines %K and nurses’ performance %R 10.21608/ejhc.2022.269544 %X Back ground: Chemotherapy is associated with several adverse effects not only for patients, butalso for nurses who handle, prepare and administer it like hair loss, skin rash and abortion. So,nurses are in urgent need of learning how to safely handle chemotherapy drugs to protectthemselves from serious complications. Aim: to enhance nurses’ performance in safe handling ofantineoplastic drugs. Methods: A quasi-experimental study was conducted involving a conveniencesample of 40 nurses working at the Fayoum Oncology Center. Data were collected using five tools:nurses’ knowledge questionnaire, nurses’ practice tool, checklist of nurses’ attitudes towardantineoplastic drugs, checklist of adverse effects caused by exposure to antineoplastic drugs, andchecklist of nurses’ opinion on the causes of noncompliance to safe handling guidelines ofantineoplastic drugs. Results: A statistically significant difference in the overall knowledge,practices, and attitude of the nurses was observed between the pre- and post-program periods (p<0.001* ). Furthermore, a positive correlation was found between nurses’ knowledge and practicesduring both the pre- and post-program periods (r = 0.582, p< 0.001* and r = 0.297, p = 0.063,respectively). Conclusion and Recommendations: Based on the results presented in this study, thenurses’ performance enhanced, which forced us to continue training and monitoring. Furthermore,medical surveillance for nurses should be implemented to assess the prevalence of complications ofantineoplastic drugs. %U https://ejhc.journals.ekb.eg/article_269544_ee56e21df250539b1576b7295b87c75b.pdf