Association between Different Types of COVID-19 Vaccines and Menstrual Cycle Patterns among Women of Reproductive Age

Document Type : Original Article

Authors

1 Women’s Health & Midwifery Nursing Department, Faculty of Nursing-Mansoura University, Egypt.

2 Registered Nurse Faculty of Nursing King Abdulaziz University Saudi Arabia

Abstract

Background: The menstrual cycle is a major aspect of a woman's general health. There were concerns that the COVID-19 vaccine could possibly alter women's menstrual cycles during the early stages of the mass vaccination campaigns. Aim: To assess the association between different types of covid-19 vaccines and menstrual cycle patterns among women of reproductive age. Design: A quantitative, cross-sectional, descriptive design Setting: The study was conducted through an online self-administered survey (google forms). Subjects: A purposive sampling was taken from an online self-administered survey, through the period from the 27th of February to the 27th of March. The sample size is over 500 Saudi women of reproductive age between 18 and 45 years. Tool for data collection: An online self-administered survey covered four parts: sociodemographic data (3 items), obstetric history (4 items), Information on the COVID-19 vaccine (3 items), and menstruation experience before and after the COVID-19 vaccine (23 items). Result: The results showed that most of the participants were aged between 18-24 years, unmarried, and had normal BMI (47.6%, 52.6% &50.7% respectively).  A menstrual disturbance was reported by (44.4%) of those who received the COVID-19 vaccination, results indicate that there was found a significant relationship between the duration of flow, menstrual blood loss, and severity of dysmenorrhea before and after receiving the first, second, and third doses of Covid19- vaccine, where the p-value of the test (0.000) was less than 0.05. Conclusion: The present study concluded that women who receive the Covid-19 vaccine may experience menstrual abnormalities, such as a significant difference in cycle length, flow duration, menstrual blood loss, and dysmenorrhea severity before and  after  receiving  the  first,  second,  and third doses of  the vaccine. While no significant difference between different types of COVID-19 vaccines (Pfizer, Moderna, and Oxford/AstraZeneca) and menstrual abnormalities. Recommendation: In view of the newly emerging phenomenon known as "long haul COVID-19," we recommend prospective studies with larger sample sizes are required to examine the long-term consequences of the different types of COVID-19 vaccination on women's reproductive health.

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