Document Type : Original Article
Authors
1
Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq. and Community Health Nursing Department, Beni-Suef Health Technical Institute, Ministry of Health, 62511, Egypt.
2
College of Medicine, Al-Mustaqbal University, 51001, Babylon, Iraq.
3
Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq.
4
Anesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001, Babylon, Iraq. and Aesthetic and Laser Techniques Department, College of Health and Medical technique, Al-Mustaqbal University, Babylon 51001, Iraq.
5
Department of Clinical Pharmacy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt
10.21608/ejhc.2025.417308
Abstract
Introduction: Propofol is a commonly used intravenous agent for the induction and maintenance of anesthesia. It possesses sedative and hypnotic properties, making it an effective choice for various surgical procedures. However, its administration is associated with certain risks, including hypotension and hemodynamic instability. Aim of study: This study aims to investigate the hemodynamic stability of patients across different age groups undergoing general anesthesia with propofol. Method: A descriptive observational study design was employed to assess hemodynamic stability in patients undergoing general anesthesia with propofol. A total of 50 patients were randomly sampled from Imam Al-Sadiq Hospital, Najaf Hospital, Alhusseiny Teaching Hospital (Karbala), and Al-Hilla Surgical Hospital. Hemodynamic parameters, including systolic and diastolic blood pressure, heart rate, and oxygen saturation, were measured pre and post-medication administration. Results and Findings: The analysis revealed a significant decrease in systolic blood pressure post-medication administration (p-value < 0.001), indicating the impact of propofol on hemodynamic stability. However, there were no significant differences in diastolic blood pressure, heart rate, or oxygen saturation pre and post-medication. The crossmatch analysis further highlighted the distribution of normal and abnormal hemodynamic signs, providing insights into the effects of propofol on specific parameters. Conclusion: There is non-significant difference between pre and post medication according to Diastolic, Heart Rate, SpO2 (p.value greater than 0.05) While there are significant differences according to Systolic. The significant reduction in systolic blood pressure post-medication suggests the efficacy of the intervention in lowering blood pressure levels Recommendations: Based on the study findings, recommendations include implementing personalized anesthesia protocols, conducting thorough preoperative assessments, and enhancing real-time hemodynamic monitoring to mitigate the risks associated with propofol-induced hypotension. Additionally, interdisciplinary collaboration and ongoing education programs can further improve patient care and safety in the perioperative setting.
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