Effect of Educational Guide on Knowledge and Quality of Life for Pemphigus Vulgaris Patients

Abdelnaby Hamed, Laila; Mohamed Abdelhamed, Hala; Mohamed Badran, Hanan

doi:10.21608/ejhc.2025.442498

Effect of Educational Guide on Knowledge and Quality of Life for Pemphigus Vulgaris Patients

Document Type : Original Article

Authors

¹ 1Assistant Professor of Medical-Surgical Nursing, Medical Surgical Nursing Department, Zagazig University, Egypt

² 2Assistant Professor of Medical-Surgical Nursing, Medical Surgical Nursing Department, Mansoura University, Egypt

³ 3Assistant Professor of Medical-Surgical Nursing, Medical Surgical Nursing Department, Mansoura University, Egypt

10.21608/ejhc.2025.442498

Abstract

Background: Pemphigus vulgaris (PV) is a chronic autoimmune disease characterized by painful and debilitating blistering of the skin and mucous membranes, which significantly disrupts patients' physical, emotional, and social well-being. Despite studies demonstrating that people with PV have a markedly lower quality of life (QOL), and despite existing interventions focusing on disease management and symptom control, there remains a notable research gap in systematically evaluating how a structured, patient-centered guide can improve the overall QOL of affected individuals. This study aimed to assess the effect of educational guide on knowledge and the quality of life for pemphigus vulgaris patients. Methods: This quasi-experimental study employed a purposive sample of 60 patients, equally divided between study and control groups. Data collection two tools were used: Tool 1 structured interview questionnaire sheet comprised two parts patients' demographic, medical data, and patients' knowledge related to disease and lifestyle activities. Tool 2 Autoimmune Bullous Disease Quality of Life Questionnaire (ABQOL). Results: Post-intervention assessment revealed that nearly two-thirds (66.7%) of the study group demonstrated a good level of knowledge, compared to one-fifth (20%) of the control group. Moreover, the study group showed substantial improvement in autoimmune bullous skin disorder quality of life scores, with the proportion of patients showing mild impact increasing from 6.6% pre-intervention to 56.7% post-intervention. Conclusions: The implementation of the nursing educational guide sessions effectively improved patients' knowledge and quality of life. Recommendations: Future research should include longitudinal studies to assess the sustainability of QOL improvements over time.

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